---

The purpose of this study was to design, implement and evaluate e-learning based on the third and fourth Paradigms of Kashman's theory. The research method was quasi-experimental and mixed (qualitative and quantitative). The statistical population of the undergraduate students of Shahid Beheshti Medical Education Faculty of Tehran was selected by sampling method available to students of medical education. The data collection tool was a questionnaire of satisfaction, motivation and period test. Their reliability was calculated 86%, 86% and 83%, respectively. The quantitative and qualitative data were analyzed using multi-variable covariance analysis, Tukey post hoc test and maxquda12 software. The results of this study showed that the effectiveness of the design was based on the third and fourth paradigms in comparison with the existing methods from the viewpoint of the students of the medical education faculty in all three variables of development, motivation and satisfaction.