Mojtaba Ahmadi, Associate Professor Gholamreza Chalabianloo, Associate Professor Reza Abdi,
Volume 13, Issue 2 (Volume 13, Issue 1, Summer 2025 2025)
The present study aimed to investigate the effectiveness of Unified Protocol (UP) and transcranial Direct Current Stimulation (tDCS) treatment on working memory and continuous attention in patients with generalized anxiety disorder (GAD). The research design employed a quasi-experimental framework, featuring a pre-test and post-test design with two experimental groups and a control group. The statistical population consisted of patients diagnosed with GAD who sought treatment at clinics and specialized neuropsychiatry centers in Tehran during the first half of 2024. Based on the inclusion and exclusion criteria, a sample of 45 individuals (31 women and 14 men) was selected through purposive sampling and equally allocated (15 individuals in each group) into the UP intervention group, the combined UP and tDCS intervention group, and the waiting list group. The Structured Clinical Interview (SCID-V), the 7-item Generalized Anxiety Disorder Scale (GAD-7), the Corsi Block Test (to assess working memory), and the Clock Test (to assess continuous attention) were utilized as assessment tools. Statistical analyses were conducted using SPSS-26 statistical software, employing analysis of covariance (ANCOVA). The findings indicated that the use of the UP protocol, both alone and in combination with tDCS, led to a significant improved in working memory and continuous attention (P<0.05). Furthermore, this study suggests that both UP intervention and the combined intervention (UP+tDCS) are effective approaches to improve working memory and continuous attention in GAD patients and may serve as a novel strategy for managing this disorder and improving executive functions.
