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Showing 3 results for Antibacterial Activity


Volume 8, Issue 4 (11-2010)
Abstract

Salvia leriifolia (Lamiaceae) is an endemic plant of Khorasan and Semnan provinces which has antinociceptive, anti-inflammatory, antidiabetic and antioxidant properties. In this research, antibacterial activity of of S. leriifolia leaf was investigated at different growth stages and the best harvesting time was determined. The leaves were harvested at vegetative (mid March), flowering (mid April) and ripening seed stages (late May). Different concentrations of metanolic extract(5,10,15 and 20 g/l) of leaves were applied on five different bacteria(Pseudomonas aeruginosa, Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli and Proteus mirabilis) according to dick diffusion method. Inhibition zones were measured after 24 hours. Inhibitory effect of extracts at different stages were compared together and with certain antibiotics (Penicillin, Ampicilin and Tetracaiclin). Statistical analysis was performed through the JMP software. Maximum antibacterial activity of leaves was coincident with flowering stage. In this stage, antibacterial activity of leaves was significantly higher than the vegetative and ripening seed stage. Inhibitory effect of leaf extract at flowering stage on some bacteria was higher than the antibiotics or similar with them. It seems that flowering stage (mid April) is the best time for obtaining the maximum antioxidant activity of leaf.
Roya Karamian, M Asadbigi, M Ranjbar,
Volume 12, Issue 3 (11-2012)
Abstract

Salvia L. is one of the important genera of the Lamiaceae family, that most of its species have nutritious and medicinal values. This study aimed to examine the total phenol and flavonoid contents and the antioxidant activities of S. aethiopis using spectrophotometric method. The essential oil of this species was analyzed using GC and GC/MS methods. In addition, antibacterial activities of the essential oil and methanolic extract were evaluated against six gram positive and negative bacteria, respectively. Results showed that the extract has high content of phenolic compounds with high antioxidant activity. From GC analysis, 11 different compounds were indentified in which &alpha-copaene was the most abundant compound with 33.48%. The extract of the species showed a high antibacterial activity against Proteus vulgaris. However, the essential oil of S. aethiopis had no effect on examined bacteria.
Roya Karamian, Davoud Ali Hosseini,
Volume 14, Issue 3 (10-2014)
Abstract

    The methanol extracts of leaves and bulbs of Allium ampeloprasum L. (Alliaceae) were analyzed for their phenolic profiles and screened for their antioxidant and antibacterial activities. Two biochemical assays, namely DPPH free radical scavenging and &beta-caroten/linoleic acid activity systems, were used to evaluate antioxidant activity. Total phenol and flavonoid contents of the species were determined by Folin-Ciocalteu and AlCl3 assays, respectively. Results indicated that the extracts are different in total phenolic content. Results from antioxidant activity showed that the extracts studied in DPPH radical scavenging assay are lower active than ascorbic acid and BHT as synthetic antioxidants. Antibacterial assay showed that the bulbs extract is more effective in inactivation of Haemophilus influenzae and Bacillus cereus and the leaves extract is more effective in inactivation of Bacillus cereus at 100 mg ml-1 than others. Then, the extracts of Allium ampeloprasum possess strong antioxidant activity and may be used as new drug supplements in the future.

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