Tarbiat Modares University , molanouri@modares.ac.ir
Abstract: (729 Views)
Introduction: Diabetes is a progressive metabolic disease that activates the immune system and increases certain inflammatory cytokines, including IL-17. One of the complications associated with diabetes affects the brain and nervous system, leading to cognitive dysfunction. Physical activities are effective in improving the condition of diabetic patients. This study aimed to investigate the effect of a multi-task combined home exercise program on serum levels of the cytokine interleukin-17 and cognitive function in women with type 2 diabetes.
Methods: Seventy patients with type 2 diabetes were randomly divided into two groups: exercise and control. The exercise group participated in a multi-task combined home-based exercise program for three months. Blood markers, cognitive function, and body composition were measured before and after the intervention. The results were analyzed using SPSS software, with a significance level of P<0.05.
Results: The present study showed that the combined exercise program led to a reduction in the inflammatory cytokine IL-17 (P<0.05). Although cognitive function showed relative improvement, the results were not statistically significant (P>0.05). Concurrently, fasting blood glucose decreased in the exercise group (P<0.05), and some body composition indices, particularly body fat percentage, improved (P<0.05).
Conclusion: Home-based combined exercise programs were associated with a reduction in the inflammatory cytokine IL-17 and a relative improvement in cognitive function in diabetic patients. The potential improvement in immune responses following these exercises may contribute to the reduction of serum IL-17 levels.
Methods: Seventy patients with type 2 diabetes were randomly divided into two groups: exercise and control. The exercise group participated in a multi-task combined home-based exercise program for three months. Blood markers, cognitive function, and body composition were measured before and after the intervention. The results were analyzed using SPSS software, with a significance level of P<0.05.
Results: The present study showed that the combined exercise program led to a reduction in the inflammatory cytokine IL-17 (P<0.05). Although cognitive function showed relative improvement, the results were not statistically significant (P>0.05). Concurrently, fasting blood glucose decreased in the exercise group (P<0.05), and some body composition indices, particularly body fat percentage, improved (P<0.05).
Conclusion: Home-based combined exercise programs were associated with a reduction in the inflammatory cytokine IL-17 and a relative improvement in cognitive function in diabetic patients. The potential improvement in immune responses following these exercises may contribute to the reduction of serum IL-17 levels.
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