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Showing 3 results for Gharakhanlou

Mohsen Alinaghizade, Reza Gharakhanlou, Mahdieh Mollanouri Shamsi,
Volume 0, Issue 0 (11-2019)
Abstract
Msc Ashkan Koushki, Professor Hamid Aghgaalinegad, Professor Reza Gharakhanlou3,
Volume 0, Issue 0 (11-2019)
Abstract

Aim: Optimal performance is the ultimate goal of athletes. The purpose of this study was to compare the effects of different high-intensity interval training (HIIT) protocols on athletic performance and metabolic adaptations. Methodes: The participants were divided into 4 groups: High-Intensity Running Training (HIITRUN), Sport-Specific High-Intensity training (HIITSPORT), Combined Training (HIITSPORT+RUN), and Control. The measured indicators included: maximum running speed in the 30-15 test (VIFT), maximum oxygen consumption (VO2max), the SWFT index and throws in the sport-specific wrestling fitness test, fatigue index, and maximal lactate. Comparisons between dependent variables were performed using a two-way analysis of variance (group and time) with repeated measures. Result: Significant changes in (VIFT) and VO2max were observed in HIITSPORT+RUN (P<0.05) and HIITRUN (P<0.05) compared to pre-training, control, and HIITSPORT. The fatigue index showed a significant decrease in HIITSPORT+RUN and HIITRUN compared to pre-training in the other groups. HIITSPORT+RUN (P<0.05) showed the greatest improvements in the SWFT index compared to HIITRUN and HIITSPORT, and the time-group interaction confirmed its superiority. Post-exercise lactate levels in HIITSPORT+RUN (P<0.05) were lower than in HIITRUN, but no significant difference was observed in the time-group interaction (P<0.05). The difference in maximal lactate levels before and after exercise in HIITSPORT+RUN (P<0.05) was lower compared to HIITRUN. HIITSPORT+RUN (P<0.05) showed better performance in the SWFT compared to pre-training. The fatigue index decreased in all training groups except for the control (P<0.05). Conclusion: the combined HIIT approach of sport-specific training and running is the most effective method for improving wrestlers' performance and metabolic adaptations.
Elmira Ahmadi, Shahnaz Shahrbanian, Mohamadreza Kordi, Reza Gharakhanlou, Gregory Pearcey,
Volume 22, Issue 27 (8-2024)
Abstract

Fatigue is one of the most common symptoms among individuals with multiple sclerosis (MS). The imbalance of inflammatory cytokines in the brain causes mental fatigue. It is believed that aerobic exercise may moderate the level of inflammation of cytokines and thus reduce mental fatigue. This study was conducted to investigate the effect of swimming aerobic training on pro-inflammatory factors (interleukin 6) and anti-inflammatory factors (interleukin 10) to evaluate mental fatigue in the brains of female mice after EAE induction. In this research, 21 mice (8 weeks old, 18 to 20 grams) were divided into three groups: healthy control, EAE control, and EAE swimming aerobic exercise. The animals in the training group performed moderate-intensity swimming exercises for 4 weeks, with 5 sessions per week, each session lasting 30 minutes. The western blot method was used to analyze the research variables. The results showed no significant difference in the amount of IL-6 between the EAE group and the swimming training group, but the amount of IL-10 in the swimming training group showed a significant increase compared to the EAE group. The ratio of IL-10/IL-6 values between the swimming training group and the EAE group was also not significant. It seems that moderate-intensity swimming aerobic exercises, without changing the pro-inflammatory factor, along with increasing the anti-inflammatory factor IL-10, can lead to an improvement in the balance of the inflammatory index and a reduction in fatigue in the EAE group and the swimming exercise group.


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