Showing 2 results for Gorzi
Khadijeh Molaei, Sanaz Mirzayan Shanjani, Ali Gorzi, Yaser Kazemzadeh, Abdolali Banaeifar,
Volume 0, Issue 0 (11-2019)
Abstract
Testosterone enanthate increases muscle growth and athletic performance but is associated with oxidative stress and tissue damage. This study aimed to investigate the effect of propolis on oxidative stress markers induced by testosterone enanthate in the kidney tissue of female Wistar rats undergoing resistance training. Twenty-two 8-week-old female rats, weighing 208.22±14.17 g, were randomly divided into three groups: 1) resistance training + placebo (n=6), 2) resistance training + testosterone enanthate (n=8), 3) resistance training + testosterone enanthate + propolis (n=8). The rats underwent an 8-week resistance training protocol involving ladder climbing (five days per week). Testosterone enanthate was administered at a dose of 20 mg/kg body weight per injection, and propolis was administered at a dose of 400 mg/kg body weight by gavage (each three times a week). The levels of superoxide dismutase (SOD), glutathione peroxidase (GPX), and malondialdehyde (MDA) in kidney tissue were measured by spectrophotometry. One-way ANOVA and Bonferroni post hoc tests were used for statistical analysis. The results showed that testosterone enanthate significantly decreased GPX and SOD levels and increased MDA levels. Propolis consumption led to a relative reduction in these oxidative stress markers, demonstrating its potential antioxidant effects.
A Gorzi, R Jazaei, A Rahmani, A Bahari,
Volume 17, Issue 18 (12-2019)
Abstract
Determining the best rest interval durations between resistance exercise sets for adaptation is very important. This study investigated the effect of different rest intervals duration between resistance exercise (RE) sets on the gene expression of CGRP and IGF-1. Forty two male Wistar rats were randomly divided in to 7 groups. The resistance exercise included one session of climbing on one meter ladder with 26 steps. Exercise included 4 sets of 5 repetitions with an overload of 150 percent of the rat's body weight and 30, 60, 90, 120, 150 and 180 seconds rest intervals. The qRT-PCR technique was used to evaluate the gene expression of CGRP and IGF-1. The gene expression of CGRP in soleus muscles following RE with rest intervals of 30 (P=0.001), 60 (P=0.001) and 90 seconds (P=0.001) were significantly lower than 120, 150 and 180 seconds. However, there were no significant differences in the gene expression of IGF-1 among all groups (P=0.12). Based on our results, it seems that these rest interval domains can be addressed as a cut point of gene expression for the strength and hypertrophy developing process at the cellular level.
