Mojtaba Salehpour, Faezeh Rezvani, Farzane Hatami,
Volume 0, Issue 0 (11-2019)
Abstract
Background: GDNF protein is involved in neurocognitive plasticity and sarcopenia, and the increase of GDNF due to resistance training leads to healthier aging and delays sarcopenia, and TRX resistance training improves the performance and morale of the elderly. The purpose of this research is the effect of six weeks of TRX training on the level of GDNF protein in the serum of elderly women.
Materials and methods: The purpose of the research is applied with a semi-experimental method including pre-test - post-test with control group and field and laboratory data. 28 elderly women aged 55 to 75 years old from the retirement center of Shahid Rajaee Tarbiat University of Tehran were randomly assigned to two experimental groups (15 people) with an average age of 60.86 ± 5.60, weight 75.00 ± 11.95, BMI ± 4.22 27.65 and six weeks of TRX training and the control group (13 people) with an average age of 64.38 ± 4.03, weight 72.69 ± 4.95, BMI 28.33 ± 2.18 and no training were divided. In the first and sixth weeks, both groups were tested for upper body strength, lower body strength and GDNF protein level by ELISA method.Shapiro-Wilk test was used to check the normality of data distribution, Levine's test for homogeneity of variances and one-way analysis of covariance test at a significance level of P < 0.05 was used to test hypotheses and statistical calculations were performed with spss24.
Results: In the results of covariance analysis of upper body and lower body strength, there is a significant difference between the two groups at the level of P <0.05. By removing the effect of the pre-test variable, there is a significant difference between the amount of GDNF protein in the experimental and control groups. By comparing the adjusted averages in the experimental and control groups, the amount of GDNF protein in the experimental group (443.102 ± 15.751) is significantly higher than the control group (209.756 ± 17.029) (P < 0.05).
Conclusion: Six weeks of TRX training had a significant effect on the amount of GDNF protein, upper and lower body strength of elderly women, and it can probably be effective in reducing or delaying sarcopenia.
