Mojtaba Salehpour, Ali Sarlak, Hadi Samadi,
Volume 21, Issue 26 (12-2023)
Abstract
Introduction: The increase of iron due to aging affects the process of ferroptosis, and the final product of lipid peroxidation, MDA, is the central regulator of ferroptosis. Therefore, the aim of the research was to determine the effect of eight weeks of endurance training on the expression of GPX4 and MDA in the soleus muscle of aged male rats.
Materials and Methods: This study is of an experimental type. 20 healthy rats were divided into two groups of 10 each: training group and control group. The training was done incrementally for eight weeks. 48 hours after the last training session, the soleus muscle of mice was surgically removed and the amount of variables was measured by gene expression and ELISA methods.
Results: There was no significant difference in the level of GPX4 gene expression in the soleus muscle of exercise group rats compared to control group rats (p=0.4079). But the amount of MDA in the training group was significantly reduced compared to the control group (p=0.0028).
Conclusion: According to the findings of the present research, it seems that the effect of endurance training in this research shows a decrease in ferroptosis. The absence of a significant difference in the level of GPX4 gene expression is a sign that endurance training with this intensity does not affect it.
Mohammad Kalantariyan, Samaneh Samadi , Ramin Beyranvand,
Volume 22, Issue 28 (12-2024)
Abstract
This research aims to investigate the changes in static and dynamic balance and proprioceptive accuracy of knee and ankle joints of young taekwondo athletes before and after applying the fatigue protocol. The current research is semi-experimental. The research subjects were 20 teenage male taekwondo players (17/86±4/4 year, 174/37±5/2 cm, 65/61±6/1 kg) from the statistical population. Static and dynamic balance variables were measured respectively by Stork's static balance test and Y dynamic balance test, as well as the proprioception of the ankle and knee joints at 10 degrees of ankle dorsiflexion and 30 degrees of knee flexion, by the photographic method. Then the functional fatigue protocol was applied. After finishing the fatigue protocol, all the variables evaluated again. The results of the paired t-test showed that after applying the fatigue protocol, there is a significant difference between the average of static (P=0.028) and dynamic balance in all three anterior (P=0.001), posterior-medial (P=0.012) and posterior-lateral (P=0.009) directions as well as proprioceptive accuracy of knee joint (P=0.003) and ankle joint (P=0.001).
It is recommended to all taekwondo coaches and athletes, to perform specialized training exercises in the field of taekwondo and according to the age of teenagers.
