Showing 44 results for Exercise
Elahe Talebi-Garakani, Shokoufeh Kheradmand, Khadijeh Nasiri,
Volume 21, Issue 26 (12-2023)
Abstract
The prevalence of obesity in postmenopausal women is higher compared to men. A decrease in estrogen with menopause leads to dysfunction in mitochondria. The purpose of this study is to investigate the effect of high intensity aerobic training(HIT) on the copy number of mitochondrial genome (mtDNAcn) and mitochondrial transcription factor A(Tfam) in visceral adipose tissue(VAT) in ovariectomized(OVX) rats fed with high-fat diet(HFD). 40 rats (8 weeks, 200±20 gr) were divided into 5 groups:1) normal diet (ND), 2) ND+OVX, 3) HFD, 4) HFD+OVX, and 5) HFD+OVX+HIT. HIT performed aerobic training (80-85% of maximum oxygen consumption) for 8 weeks/5 sessions/42 minutes.48 hours after the last training session, VAT samples were taken to evaluate mtDNAcn and Tfam gene expression by qRT-PCR method. ANOVA and LSD tests were used to compare the differences between groups. OVX and HFD didn’t lead to a significant change in Tfam gene expression, but caused a significant decrease in the mtDNAcn compared to the control group. HIT caused a significant increase in Tfam gene expression compared to the control group and Tfam gene expression and mtDNAcn compared to the HFD+OVX. Hence, HIT improves mitochondrial function through mtDNAcn and Tfam gene expression in VAT in OVX rats fed by HFD.
Elmira Ahmadi, Shahnaz Shahrbanian, Mohamadreza Kordi, Reza Gharakhanlou, Gregory Pearcey,
Volume 22, Issue 27 (8-2024)
Abstract
Fatigue is one of the most common symptoms among individuals with multiple sclerosis (MS). The imbalance of inflammatory cytokines in the brain causes mental fatigue. It is believed that aerobic exercise may moderate the level of inflammation of cytokines and thus reduce mental fatigue. This study was conducted to investigate the effect of swimming aerobic training on pro-inflammatory factors (interleukin 6) and anti-inflammatory factors (interleukin 10) to evaluate mental fatigue in the brains of female mice after EAE induction. In this research, 21 mice (8 weeks old, 18 to 20 grams) were divided into three groups: healthy control, EAE control, and EAE swimming aerobic exercise. The animals in the training group performed moderate-intensity swimming exercises for 4 weeks, with 5 sessions per week, each session lasting 30 minutes. The western blot method was used to analyze the research variables. The results showed no significant difference in the amount of IL-6 between the EAE group and the swimming training group, but the amount of IL-10 in the swimming training group showed a significant increase compared to the EAE group. The ratio of IL-10/IL-6 values between the swimming training group and the EAE group was also not significant. It seems that moderate-intensity swimming aerobic exercises, without changing the pro-inflammatory factor, along with increasing the anti-inflammatory factor IL-10, can lead to an improvement in the balance of the inflammatory index and a reduction in fatigue in the EAE group and the swimming exercise group.
Fatemeh Kazeminasab, Mohammad Hossein Mahboobi, Karim Azali Alamdari,
Volume 22, Issue 27 (8-2024)
Abstract
The purpose of this study was to investigate the impact of combining aerobic exercise (AE) and vegetarian diet (VD) on blood pressure and body weight in adults with overweight and obesity. The PubMed, Web of Science, Scopus, and Google scholar databases were searched until February 2023 for English articles, and 1065 articles were found. Meta-analyses were performed to compare the impact of aerobic exercise and vegetarian diet on body weight, blood pressure in adults with overweight and obesity. Data analysis was performed using random effect model and weighted mean differences (WMD). The results of meta-analysis of 25 studies with 10192 adults showed that combined aerobic exercise and vegetarian diet significantly decreased in body weight [WMD=-4.63, p=0.001] , systolic blood pressure [WMD=-6.94, p=0.001] , and diastolic blood pressure [WMD=-4.5, p=0.001] , in adults with overweight and obesity. Aerobic training alongside vegetarian diet as a non-medication approach for weight loss and blood pressure control in adults with overweight and/or obesity. In addition, aerobic exercise and vegetarian diet with both types of duration (less than 12 weeks and more than 12 weeks) cause a significant decrease in blood pressure in adults with overweight and obesity.
Dr Amir Letafatkar, Faranak Amini, Bahram Sheikhi,
Volume 22, Issue 27 (8-2024)
Abstract
Introduction: The aim of this study was to compare the effectiveness of a combination of pain neuroscience education and targeted cognitive motor control training with targeted cognitive motor control training alone in patients with chronic low back pain.
Materials and Methods: Fifty-four chronic low back pain patients (pain neuroscience education with targeted cognitive motor control training group, n=27 and targeted cognitive motor control training only group, n=27) participated in this study. Pain, disability, central sensitization inventory, and kinesiophobia were assessed at baseline and eight weeks after interventions. Repeated measures analysis of variance and linear mixed models were used to examine between-group differences.
Results: A significant group×time interaction effect was found for pain (p=0.008), central sensitization inventory (p=0.002) and kinesiophobia (p<0.001) in the pain neuroscience education with targeted cognitive motor control training group compared to the targeted cognitive motor control training only group after eight weeks. Main effects of time were observed for pain, disability, and fear of movement after interventions (p<0.001). No significant group×time interaction effects was found for disability (p=0.50).
Conclusions: This study’s findings support the provision of pain neuroscience education as a clinically effective addition to targeted cognitive motor control training in chronic low back pain patients.
