Showing 5 results for Exercise Training
, ,
Volume 11, Issue 5 (3-2013)
Abstract
improves insulin resistance. However, the effect of training sessions a day is not
clear in this regard. The aim of this study was to investigate the effect of one or
two sessions a day of exercise training, with equal intensity and duration, on
insulin resistance in sedentary middle-aged men. Materials & Methods: 30
sedentary middle-aged male volunteers (age=43.6±6.5 yr, weight=80.4±13.6kg,
height=174.1±5.5cm,BMI=26.5±3.6kg/m2،VO2max=35.46±6ml/kg) randomized to
the control (n=10), one session a day (n=10)and two sessions a day training
group( n=10). Exercise program consisted of 16 weeks, five days a week, tread
mill running which was implemented as one (30 minutes) or two sessions (2×15
minutes) a day. Training intensity was 40-50% of HRmax at first week and
reached to 70-80% at 16th week of the training. Measurements of fasting blood
samples (insulin, glucose and adiponectin), insulin resistance, cardiorespiratory
fitness, abdominal obesity and BMI were obtained at baseline and post
exercise. Paired t test and analysis of Variance were used to analyze the data.
Results: After 16 weeks of training, compared with the control group, a
significant reduction in blood glucose, abdominal obesity and BMI, and a
significant increase in cardiorespiratory fitness were observed in the both
experimental groups; whereas insulin resistance remained unchanged, and
adiponectin was significantly increased only in the one session a day training
group. Conclusion: based on the findings it seems that, dividing the physical
activity session in two shorter parts can improve glucose profile, cardiorespiratory
fitness and obesity indicators the same as a continuous exercise session. But in
terms of increased adiponectin and decreased abdominal obesity, continuous
exercise session is more effective.
Zahra Mohammadpour , Karim Azali Alamdari, Azam Zarneshan,
Volume 18, Issue 20 (11-2020)
Abstract
There is a large necessity for met analytic investigation of the blood pressure (BP) response to aquatic exercise training (AET) in hypertensive patients. was to quantify BP changes after (AET) and identify subgroups exhibiting the largest changes. Clinical trials investigating the impact of AET on hypertensive patients published in English and Persian research journals up to July 2020 were searched from google scholar, Pubmed, Science Direct, SID and magiran. Finally, 12 trials were analyzed to quantify effect sizes (difference in means with 95% confidence intervals) using Random Effects model. Subgroup analyses included gender, menopause status, number of sessions per week and training intensity categories. Simple random-effects meta-regression analysis (methods of moment approach) was performed to investigate the association between changes in BP and changes in both training duration and water temperature. AET decreased both SBP and DBP; -12/29 and -5/69 mm Hg respectively, regardless to hypertensive subjects’ characteristics, training session count per week and water temperature. A tendency for larger reductions in SBP with greater reductions in body weight (β1=0.38, P=0.003) and water temperature (β1=1-.29, P=0.012) were observed after AET. In addition, the magnitude of the effect of AET on both SBP and DBP were significant in all subgroups (except for SBP in males) (P <0.05). AET remarkably lowers both SBP and DBP in hypertensive emphasizing on the clinical importance of AET in controlling hypertension. Likewise; it seems more BP reductions could be inevitable in patients with lower body weight and also elevations in water temperature (up to 38 °C). However, more clinical trials still need to be provided because of the lack of evidence and also heterogeneity of the results.
Dr Ali Asghar Ravasi, Dr Mousa Khalafi, Dr Karim Azali Alamdari,
Volume 19, Issue 22 (12-2021)
Abstract
Background and objective: Effects of exercise training on metabolic disorders through modifications in fibroblast growth factor -21 (FGF-21) level are controversial. Therefore, the aim of study was to determine the quantitative effect of exercise training protocols on serum FGF-21 level in adults with metabolic disorders. Methods: A systematic search of the published Persian or English-language studies from PubMed and Google Scholar databases up to march 2021 was done and standardized mean differences (SMDs) were calculated using random-effects models. Results: a total of 14 studies (aerobic training=3, resistance training=3, HIIT=4, concurrent training=4) including on 19 interventions conducted on 503 subjects (with overweight, obesity, type 2 diabetes, metabolic syndrome and or fatty liver disease) were eligible to include in the meta-analysis. However, because of the heterogeneity, the final quantitative impact of 16 interventions was calculated as a declining serum FGF21 level after training [SMD=-0.44(CI: -0.65 to -0.22) p=0.001] which had no correlation with subjects age(p=0.10) or BMI(p=0.50) level. Conclusion: exercise training protocols are efficient tools for a remarkable decrease in serum FGF-21 in patients with metabolic disorders which seems to lead to more beneficial effects on metabolic disturbances. However, more clinical trials are still warranted in this area considering the role of exercise components such as exercise intensity and type
Dr Majid Kashef, Dr Maral Ramez, Azam Ahmadi,
Volume 20, Issue 24 (3-2023)
Abstract
It is estimated that by 2035, more than 130 million adults will suffer from various types of cardiovascular diseases. Therefore, it is very important to know the pathogens of cardiac diseases and investigate new treatments. Also, despite continuous progress in diagnosis, patient education, and risk factor management, myocardial infarction (MI) remains one of the most common causes of morbidity, hospitalization, and mortality worldwide. The events associated with MI are highly complex and characterized by rapid metabolic and biochemical changes. Exercise training is an effective cardioprotective strategy that reduces adverse effects of MI and ischemia/reperfusion (I/R). Multiple signaling pathways of exercise preconditioning in mitigating MI-induced cardiac damage is one of the topics that has attracted much attention. In this article, some of the contributing factors in exercise-induced cardiac protection, including mitochondrial changes, metabolic changes, vascular adaptations, antioxidant capacity, heat shock proteins, cyclooxygenase levels, ATP-sensitive potassium channels, adenosine, protein kinase C, calcium and klotho homeostasis are discussed.
Elahe Talebi-Garakani, Shokoufeh Kheradmand, Khadijeh Nasiri,
Volume 21, Issue 26 (12-2023)
Abstract
The prevalence of obesity in postmenopausal women is higher compared to men. A decrease in estrogen with menopause leads to dysfunction in mitochondria. The purpose of this study is to investigate the effect of high intensity aerobic training(HIT) on the copy number of mitochondrial genome (mtDNAcn) and mitochondrial transcription factor A(Tfam) in visceral adipose tissue(VAT) in ovariectomized(OVX) rats fed with high-fat diet(HFD). 40 rats (8 weeks, 200±20 gr) were divided into 5 groups:1) normal diet (ND), 2) ND+OVX, 3) HFD, 4) HFD+OVX, and 5) HFD+OVX+HIT. HIT performed aerobic training (80-85% of maximum oxygen consumption) for 8 weeks/5 sessions/42 minutes.48 hours after the last training session, VAT samples were taken to evaluate mtDNAcn and Tfam gene expression by qRT-PCR method. ANOVA and LSD tests were used to compare the differences between groups. OVX and HFD didn’t lead to a significant change in Tfam gene expression, but caused a significant decrease in the mtDNAcn compared to the control group. HIT caused a significant increase in Tfam gene expression compared to the control group and Tfam gene expression and mtDNAcn compared to the HFD+OVX. Hence, HIT improves mitochondrial function through mtDNAcn and Tfam gene expression in VAT in OVX rats fed by HFD.
