Showing 4 results for Hypoxia
Dr Rasoul Eslami,
Volume 0, Issue 0 (11-2019)
Abstract
Introduction: Blood flow restriction (BFR) has been shown to induce local hypoxia. Therefore, the purpose of this study was to investigate the effect of BFR-induced hypoxia on the angiogenic response to high-intensity interval exercise (HIIE). Methods: Thirty active young men (age =25.6±3.4) were randomly assigned to three groups (n=10 each): control, high-intensity interval exercise (HIIE), and high-intensity interval exercise with blood flow restriction (HIIE+BFR). The HIIE protocol consisted of 5 sets of 5×30-second high-intensity running intervals with 30-second rest periods. BFR was applied at 60% of each individual's optimal occlusion pressure in the lower limbs. Serum levels of VEGF, HIF-1α, MMP-9, and MMP-2 were measured as angiogenic markers. Statistical analysis was performed using ANCOVA with LSD post-hoc test, with the significance level set at α=0.05. Results: The data revealed that compared to both the control and HIIE groups, the HIIE+BFR group showed significantly greater increases in serum VEGF and HIF-1α levels (P=0.002 and P=0.019, respectively). However, no significant differences were observed among groups for MMP-9 and MMP-2 levels (P=0.318 and P=0.101, respectively). Conclusion: This study demonstrated that combining HIIE with BFR can enhance the angiogenic response through increased VEGF and HIF-1α levels, but does not significantly affect MMP-2 and MMP-9. These findings support the notion that BFR-induced local hypoxia may serve as a complementary stimulus for improving vascular adaptations.
Mr Hamid Reza Barzegar Pour, Dr Fariborz Hovanloo, Dr Hamid Rajabi, Mr Naser Asgarzadeh,
Volume 14, Issue 11 (4-2016)
Abstract
The aim of the present research is comparing the effectof periodic trainingin hypoxic and normoxic conditions on anaerobic performance of athletes .Subjects of this research were 16 male volunteer students.Subjects were divided to two groups of eight by exercising in hypoxic condition(H 3300) normocytic.Anaerobic performance (peak power, average power) through the Wingate test and lactate concentration were measured before and after the Wingate test.After 24 hours in hypoxic condition,and after 48 hours in normoxic condition the measures of W max were determined.The intensity of exercises in both groups (one minute with intensity of 80% -85% Wmax, and two minutes with 50% Wmax) and exercise duration (30 minutes)were equalized. The training program consisted of 12 sessions in a row. After that the pre-test variables were measured again .After testing the normal distribution given by Kolmogorov – Smirnov test, dependent and independent t-Test with a confidence level of 0.05 ≥ p showed that this training improved aerobic performance in both groups, also five minutes after the Wingate test lactate concentration was decreased in both groups, but there was no difference between the 12 sessions of the periodic training in hypoxic and normoxic conditions on anaerobic performance. So it can be stated that the training used in this study can improve the anaerobic performance, but the severity and duration of hypoxia used in this study was not so much to improve anaerobic performance in hypoxic group more than normocyticone
Danial Timaji, Farshad Ghazalian, Mandana Gholami, Hossein Abednatanzi,
Volume 22, Issue 28 (12-2024)
Abstract
In order to remain competitive, athletes and coaches are constantly looking for ways to enhance performance. The aim of this study was to investigate the effect of HIFT training and hypoxia mask on maximum oxygen consumption and respiratory efficiency of the players of Iran's men's national ice hockey team. In this semi-experimental study, 14 players of the Iranian national ice hockey team were divided into two HIFT and HIFT exercise with hypoxia mask groups, then both HIFT groups and HIFT exercise with hypoxia mask, performed HIFT training sessions with 30 seconds repetition and five sets for about an hour, three sessions a week for six weeks. maximum oxygen consumption (VO2max) and respiratory efficiency (vE/VCO2) were measured using gas analyzer. The results showed that HIFT and HIFT with hypoxia mask have an increasing effect on VO2max, but there was no difference between the effect of HIFT and HIFT with hypoxia mask on VO2max (P=0.390). vE/VCO2 decreased in both groups, but there was no difference between the effect of HIFT training and hypoxia mask on vE/VCO2 (P<0.05).
According to the similar respiratory performance benefits, elite male ice hockey players can benefit from HIFT training.
Sajad Karami, Hamid Rajabi, Fereshteh Shahidi, Fereshteh Golab,
Volume 23, Issue 29 (7-2025)
Abstract
Introduction and purpose: Age-related changes in the expression of angiogenesis-stimulating and inhibitory genes are characteristics of aging and endothelial dysfunction. Aerobic exercise can stop or reduce this disorder. Considering the importance of resistance training in the rehabilitation of the elderly, the aim of this study was to investigate the compatibility of the response of the stimulating and inhibiting factors of angiogenesis after resistance exercise intervention in the elderly. Methodology: 24 elderly men with an average age of 67.75 years were selected in an accessible and purposeful manner. Blood samples were taken before and after a resistance activity session before and after 8 weeks of resistance training. Real Time PCR method was used to express HIF-1, VEGF, SDF-1 and VEGI genes in blood tissue. The difference in the values of the variables was evaluated by the method of analysis of variance with repeated measurement of mixed design at the level of P≤0.05 using SPSS software version 25. Findings: HIF-1, VEGF and SDF-1 gene expression levels of the training group increased in the stages of the primary post-test (after one session), secondary pre-test and secondary post-test (after 8 weeks of training) and VEGI had no gene expression. Discussion and conclusion: It can be cautiously said that although one session of resistance training leads to gene expression of angiogenesis factors, long-term resistance training with sufficient intensity and volume can It activates the rate of angiogenesis in a much wider range and should be considered as a supplement to aerobic exercises in old age.
