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Showing 6 results for Lactate

Dr Sajad Karami, Dr Hamid Rajabi, Dr Majid Kashef, Dr Mohammad Ali Gharaat,
Volume 0, Issue 0 (11-2019)
Abstract

Introduction and purpose: The present study was conducted with the aim of investigating the effect of acute glutamine supplementation along with intermittent exercise on Hsp70 and blood lactate response of club football players. Methodology: 32 players of the Tehran Railway team were selected and randomly divided into four groups: control, supplement, supplement-sports activity, and sports-activity. Subjects participated in daily exercises before conducting the study, and only two complementary groups - sports activity and sports activity - performed the periodic protocol. Blood samples were taken at baseline, pre-test, post-test and 90 minutes after the test. The supplement and placebo were consumed in an amount of 0.5 g/kgBW and a volume of 5 ml/kgBW one hour before the periodic protocol. The interval protocol included 3 stages of 20-minute running with an intensity of 80% of the maximum heart rate and a 5-minute rest of walking between the stages. HSP72 and blood lactate levels were measured using ELISA and enzymatic methods, respectively. The data were analyzed using the analysis of variance test with repeated measures and the between-group factor at the P≤0.05 level. Findings: Glutamine supplement alone and together with exercise stimulate the response of HSP72 and the combination of supplement and exercise leads to a greater response of HSP72 and lactate changes did not play a role in this response. Discussion and conclusion: It seem that taking glutamine supplements in the long term creates more adaptations, which of course should be studied.
 
, , , ,
Volume 9, Issue 1 (3-2011)
Abstract

In order to compare the acute effects of OR and Megabasic (two energy drinks)
by a placebo, 24 volunteer male athletes (age: 24.3±2.03 yrs, height
173.56±7.02cm and weight 75.43±3.07kg) participated in two consecutive
RAST tests by 40 min rest interval in between within 3 randomly divided groups.
There were six times blood sampling (before and also 2 and 4 min after than
both tests) in order to analyze blood lactate and PH levels (Gas analyzer) and
also the anaerobic indices (Peak, mean and mean power) was calculated. The
data corresponding to each group’s blood factors was compared by ANOVA for
repeated measurements (post hoc: Bonferoni), their changes between two
consecutive RAST tests was compared by ANOVA (post hoc: LSD) and
anaerobic power data for each group was compared using pair sample t test at
0.05 significance level. Results: Significant changes were observed in blood
lactate and PH levels during repeated measurements in both RAST tests at all
groups (p<0.05). There were also significant differences in the amount of the
changes in between the measurements between groups (p<0.05). Additionally,
Peak and min power only significantly increased in second RAST test rather
than first one and mean power also significantly decreased in both energy drink
groups between the first and second RAST tests (p<0.05). Conclusions:
Consumption of the OR can affect anaerobic power during short term repeated
interval activities. However, there are evident differences in between multiple
brands of energy drinks with regard to the amount of the modifications in the
changes at both blood lactate and PH levels, in spite of this fact that there is
any consensus in this field because of the lack of comprehensive researches.


, , ,
Volume 9, Issue 1 (3-2011)
Abstract

This study investigated the effect of water immersion and passive recovery on blood lactate and subsequent swimming performance. Ten trained female swimmers, age (17.8 ±2.2), height (164.55.8 cm), weight (59.29.9 kg), %BF (22.41.7) and BMI (21.85.4kg/m2) completed three experimental trials differing in 15 min recovery intervention three times a week with 48 hrs distance: land (sitting near the pool) (PAS), contrast water therapy (CWT) (alternating hot 40,2 min/cold 23,1min) and cold water immersion(CWI)(23 ). Before and after 100meters front crawl and each three
minute during of recovery blood lactate, heart rate and skin temperature were
recorded. Participants repeated 100meters front crawl after the recovery.
Repeated measure and LSD were used for data analysis. In all statistical
analyses, the threshold for significance was set at (p≤0.05). Results showed
that Heart rate decreased significantly in CWI toward PAS. Lactate removal was
largest in CWT compared to the PAS. Skin temperature and fatigue decreased
significantly after immersion and significant difference was observed in
subsequent performance after immersion toward PAS. So it seems immersion
conditions, can enhance quality of recovery.


Ali Molaei , Sedigheh Hosseinpour Delavar, Ghahramani Mehran, Reza Jabbari, Mohammad Jalilvand,
Volume 18, Issue 20 (11-2020)
Abstract

The present study was aimed to determine the effect of cold-water immersion and (TDCS) during the recovery period on blood lactate changes in and subsequent performance of professional male swimmers. For this purpose, 20 male participated in this study in two days with an interval of 48 hours. The two-hundred meter breaststroke was performed every day and then the subjects participated in one of the protocols, an anodic stimulation (with intensity of 2 mA)or the artificially exposed to anodic stimulation on the first day, and on the second day they were experienced the cold water immersion (12° C).The subjects' blood lactate was measured. Finally, in order to measure the effect of the investigated methods on their performance, the 200-meter swim was repeated. To analyze the data dependent t-test and analysis of covariance, LSD follow-up, analysis of variance with repeated measures, were used. The results of this study indicated that swimming performance significantly improved only in the TDCS group, with a reduction in the record time (P = 0.001). Blood lactate showed a greater decrease in the cold water immersion group (P = 0.001)

Dr Rasul Eslami, Navab Abnama,
Volume 20, Issue 24 (3-2023)
Abstract

The aim of the present study was to investigate The effect of HMB-FA supplementation on the muscle damage markers after soccer matches. 24 male soccer players (age: 23±3 years, BMI: 22.8±2 kg/m2) were voluntarily selected as the statistical sample of this study and were divided into two Suppplement and Placebo groups (n=12). In this study, subjects participated in a weekly soccer microcycle with two matches. Subjects in the supplement-training group consumed three grams of HMB-FA daily during a weekly soccer cycle. Blood samples were taken in seven times (before supplementation, before the first match, immediately after the first match, 24 hours after the first match, before the second match, immediately after the second match, 24 hours after the second match). Plasma concentrations of creatine kinase (CK) and lactate dehydrogenase (LDH) were measured by ELISA kits. Data analysis was performed using Friedman, Wilcoxon, Kruskal-Wallis and U Mann-Whitney tests with a significance level of p ≥ 0.05. After supplementation, a significant decrease in plasma levels of lactate dehydrogenase (before and after the first match) and creatine kinase (in the times immediately after the first match and before the second match) was observed (for all, p <0.05). Intaking HMB-FA supplement reduced the markers of muscle damage, which is essential for recovery from injuries caused by training and competition during a two race cycle. In addition, inaking HMB-FA supplement may have other effects, including reducing neuromuscular fatigue, reducing the inflammatory response, and rapid skeletal muscle regeneration, which requires further study.

Dr Malihe Aveseh, Dr Maryam Koushkie Jahromi, Dr Javad Nemati, Dr Saeed Esmaeili Mahani,
Volume 21, Issue 25 (9-2023)
Abstract

Lactate has been recently considered as a signaling factor involved in metabolism. The aim of this study was to investigate the role of lactate entrance into the brain on endurance training-induced adaptations in lipid oxidation. 
24 male rats (age: 8 weeks, weight: 197 ± 21 g) were divided into control (C), trained (T), and traind+4-CIN (T+4-CIN, which experienced the inhibition of lactate entrance into the brain during exercise). All animals performed a single session of acute endurance exercise following their 12-weeks training protocol.  Free fatty acids (FFA) and triglyceride content in plasma and adipose tissue and cAMP and Inositol triphosphate (PI3) content in epididymal fat were measured immediately after acute exercise using ELISA and were compared among the groups by one-way analysis of variance (ANOVA).
Acute exercise significantly increased lactate concentration in cerebrospinal fluid (SCF) in both T and T+4-CIN compared to the C group. Lactate concentration was slightly lower in T + 4-CIN compared to the T.  Immediately after acute endurance training, a significant decrease of 61 and 31% in plasma triglyceride levels, a significant decrease of 39 and 26% in adipose tissue triglyceride levels, a significant increase of 125 and 56% in plasma FFA levels, a significant increase of 217 and 125% increase in FFA plasma levels, a significant increase of 87 and 41% in adipose tissue cAMP levels, and a significant increase of 90 and 49% in adipose tissue inositol triphosphate levels was observed in the T and T+4-CIN compared to the control group, respectively (all P < 0.01). Plasma triglyceride and adipose tissue levels in the 4-CIN + training group were significantly higher and plasma and adipose tissue FFA levels were significantly lower (all P < 0.05) than the values found in the T group.  In conclusion, the results of the present study showed that lactate can be effective on endurance training-induced adaptations in lipid oxidation due to its action in the brain.


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