Protective Role of Wheat Sprout Extract on Histological and Histometric Structure of Ovary in Rats Exposed to Lead

hadijafari, mehdi; morovvati, Hassan; armand, nezam

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Protective Role of Wheat Sprout Extract on Histological and Histometric Structure of Ovary in Rats Exposed to Lead

Mehdi Hadijafari

, Hassan Morovvati ^*

, Nezam Armand

Faculty of Veterinary Medicine, University of Tehran , hmorovvati@ut.ac.ir

Abstract: (568 Views)

Herbs such as wheat sprout are rich in antioxidants including vitamin E, thiamine, zinc, phenolic acids, alkylresorcinols, aminophenol and aminobenzoic acids. We investigated the protective effect of wheat sprout extract against lead acetate treatment of ovaries. Lead toxicity causes body weakness, disability and mental performance in children, deafness and blindness, reduction in sperm quality and decreased female fertility. We used 30 female adult Wistar rats divided into six groups: untreated control, 10 mg lead, 100 and 200 mg wheat sprout extracts, and lead plus 100 and 200 mg wheat sprout extract. In comparison to control grpoup, The weight of the rat and ovaries were reduced in the 10 mg lead treated and the thickness of the inner and outer part of the ovarian capsule, and diameter and number of follicles were reduced, while the number of atretic follicles was increased. Wheat sprout extract can reverse the damage caused by lead in a dose dependent manner.

Keywords: Histology, Ovary, Antioxidants, Triticum