Comparing the effectiveness of mindfulness-based stress reduction therapy (MBSR) with intensive short-term dynamic psychotherapy (ISTDP) on reducing obsessive-compulsive symptoms and improving treatment adherence in patients with nonalcoholic fatty liver disease

Zeidabadinejad, Mohammad Mehdi; torabi, ahmad; mohammadifar, fatemeh; nori, zahra; tovakoli, roya

Volume 19, Issue 3 (Volume19, Issue 3 2025) 2025, 19(3): 0-0 | Back to browse issues page

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Zeidabadinejad M M, torabi A, mohammadifar F, nori Z, tovakoli R. Comparing the effectiveness of mindfulness-based stress reduction therapy (MBSR) with intensive short-term dynamic psychotherapy (ISTDP) on reducing obsessive-compulsive symptoms and improving treatment adherence in patients with nonalcoholic fatty liver disease. Research in psychological health 2025; 19 (3)
URL: http://rph.khu.ac.ir/article-1-4769-en.html

Comparing the effectiveness of mindfulness-based stress reduction therapy (MBSR) with intensive short-term dynamic psychotherapy (ISTDP) on reducing obsessive-compulsive symptoms and improving treatment adherence in patients with nonalcoholic fatty liver disease

Mohammad Mehdi Zeidabadinejad

, Ahmad Torabi¹

, Fatemeh Mohammadifar

, Zahra Nori

, Roya Tovakoli

1- , torabi@gmail.com

Abstract: (945 Views)

The aim of the present study was to compare the effectiveness of Mindfulness-Based Stress Reduction (MBSR) and Intensive Short-Term Dynamic Psychotherapy (ISTDP) on obsessive-compulsive symptoms and treatment adherence in patients with non-alcoholic fatty liver disease. This study employed a quasi-experimental design with a pretest, posttest, and one-month follow-up, including a control group. The statistical population consisted of patients with non-alcoholic fatty liver disease who were referred to specialized gastroenterology and liver centers in Tehran in 2025. A total of 48 participants were selected using purposive sampling and were randomly assigned to three groups: Mindfulness-Based Stress Reduction, Intensive Short-Term Dynamic Psychotherapy, and a control group. Ultimately, the data of 45 participants were analyzed. The experimental groups received eight 90-minute intervention sessions, whereas the control group was placed on a waiting list. Data were collected using the Maudsley Obsessive-Compulsive Inventory (MOCI) and the Morisky Medication Adherence Scale (MMAS) and were analyzed using repeated-measures analysis of variance and the Bonferroni post hoc test. The findings indicated that both interventions significantly reduced obsessive-compulsive symptoms and increased treatment adherence compared with the control group. Furthermore, Mindfulness-Based Stress Reduction demonstrated greater effectiveness than Intensive Short-Term Dynamic Psychotherapy in reducing obsessive-compulsive symptoms and improving treatment adherence, and these effects remained stable at the follow-up assessment. Overall, both therapeutic approaches were effective in improving the psychological status of patients with non-alcoholic fatty liver disease; however, Mindfulness-Based Stress Reduction showed superior effectiveness.

Keywords: Non-alcoholic fatty liver disease, Mindfulness-Based Stress Reduction, Intensive Short-Term Dynamic Psychotherapy, Obsessive-compulsive symptoms, Treatment adherence.