The present study aimed to predict pain tolerance based on spiritual health and self-control in patients with cancer. Cancer is often accompanied by chronic and debilitating pain, and identifying psychological factors that influence pain tolerance can play a key role in improving patients’ quality of life. Since spiritual health and self-control are fundamental components of psychological adjustment to physical and emotional stress, examining their effects on pain tolerance can provide a new approach for psychological interventions among cancer patients. The research method was descriptive-correlational. The statistical population included all cancer patients who referred to Namazi Hospital in Shiraz in 2024 (N = 260). Based on Morgan’s table, a sample of 150 patients was selected using the available sampling method. The instruments included the Pain Tolerance Questionnaire by Sullivan et al. (1995), the Spiritual Well-Being Scale by Paloutzian and Ellison (1982), and the Self-Control Scale by Tangney (2004). Data were analyzed using SPSS software and multiple regression analysis. The results indicated that both religious well-being and existential well-being positively and significantly predicted pain tolerance. Furthermore, self-control was positively and significantly associated with pain tolerance and contributed significantly to the explained variance. These findings suggest that spiritual health and self-control are important factors in enhancing resilience and psychological adjustment among cancer patients facing pain and suffering, highlighting the need to consider these variables in psychological and clinical care programs.
