In an agricultural system, crop production is related to climatic conditions. Therefore, a deeper understanding of the impact of regional climate change on production ensures global food security. Wheat is one of the most strategic crops and examining different aspects of its production is a necessity of every agricultural community. According to studies, wheat production is affected by various variables including environmental, individual and social, economic and technological. The aim of this study was to estimate the effect of these variables on changes in wheat production in different climates of Fars province. The required data were collected and analyzed through multi-stage random stratified sampling and 522 completed questionnaires through face-to-face interviews with farmers in the province. Farmers' attitudes were measured in the Likert scale and Cobb Douglas, Transcendental and Translog production functions were used to estimate the effect of variables. Results of comparing effective variables in three Cobb-Douglas, Transcendental and Translog functions; demonstrates the superiority of translog. From the perspective of the farmers of the province in the translog function, respectively; Soil moisture at planting time (0.692), effective rainfall during growing season (0.68) and at planting date (0.66), heat wave at harvest time (0.63), damaging rainfall (0.59) , Profit from wheat production (0.51), farmer education (0.49), soil quality (0.49) and cultivation method (0.49) with the coefficient of the mentioned criteria next to them; The most important factors explaining wheat production in Fars province. Independent variables in the translog function explain 92% of the changes in wheat production in Fars province.