In recent decades, one of the main challenges in regional development studies is trying to understand the economic and cultural differences between the national and regional levels, so that the obstacles facing regional development can be removed. One of the systems that plays an important role in the development of regions is the regional innovation system. For this purpose, the aim of the current research is to identify the key drivers effective on regional innovation in the metropolis of Tabriz. In this regard, the current research is applied in terms of purpose and descriptive-analytical in terms of nature. In order to collect the required information, both library and field methods have been used. The statistical population of the research includes 32 qualified people in the industry, university and government sectors who were selected by purposeful sampling. Mic Mac software was also used for data analysis. The findings of the research show that out of a total of 71 influential factors, 13 factors include the appropriate culture of productivity, laws and regulations, the existence of a teamwork culture between activists and established industrial units, information and communication technology infrastructure, sufficient funding for university research infrastructure, and higher education. patent programs, higher education policy, performance evaluation and reward system, financial support, special and flexible tax system for research and development, the existence of joint research centers between universities and industry and the level of interaction and cooperation between universities and industry, a key role in innovation They have an area of Tabriz metropolis.
