Effects of 12-week integrated exercise training on glycemic and peripheral sensation control in diabetic peripheral neuropathy

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Volume 19, Issue 22 (12-2021) RSMT 2021, 19(22): 113-129 | Back to browse issues page

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Effects of 12-week integrated exercise training on glycemic and peripheral sensation control in diabetic peripheral neuropathy. RSMT 2021; 19 (22) :113-129
URL: http://jsmt.khu.ac.ir/article-1-424-en.html

Effects of 12-week integrated exercise training on glycemic and peripheral sensation control in diabetic peripheral neuropathy

Abstract: (2400 Views)

Aim: Neuropathy control and management is an objective in therapeutic exercises prescribed for patients with Type 2 diabetic peripheral neuropathy. We examined the effects of 12-week integrated exercises (IE) on glycemic control and peripheral sensation criteria in patients with diabetic neuropathy. Methods: Based on scores of MNSI, we assigned 40 patients into two equal paired random groups (control vs. IE). Pre and post-tests were administered before and after three months of intervention for 3 sessions per week with a time of 60 minutes in the first week and gradually increased with the duration and volume of training to 90 minutes in the final session.
Results: Repeated measures ANOVA showed no significant interaction between FBS of the groups (P = .26), but significant interactions were observed between the levels of 2 hrs pp G , 4 pm G, HbA1c, Diapason, Monofilament, and Thermofeel in favor of the IE group (P <.05). Conclusion: At the beginning of the IE, we used massage and foam roller to release pain, and improve blood circulation as well as sensation in the neuropathic areas. This may have helped the patients perform the aerobic and resistance exercises more easily Therefore, better glycemic control and peripheral sensation was achieved. Verification of the long-term effects of this training strategy requires further study.

Keywords: Diabetic Neuropathies, Diabetes Mellitus (Type 2), Exercise Therapy, Blood Glucose, Michigan Neuropathy Screening Instrument (MNSI)

Full-Text [PDF 1165 kb] (1267 Downloads)

Type of Study: Research |
Received: 2020/07/11 | Accepted: 2020/11/15 | Published: 2021/12/22

References

1. Boulton, A.J. (2005). Management of diabetic peripheral neuropathy. Clinical Diabetes. 23(1): 9-15. [DOI:10.2337/diaclin.23.1.9]

2. Guariguata, L., Whiting ,DR., Hambleton, I., Beagley, J., Linnenkamp,‌ U., Shaw JE. (2014). Global estimates of diabetes prevalence for 2013 and projections for 2035. Diabetes Research and Clinical Practice. 103(2): 137-49. [DOI:10.1016/j.diabres.2013.11.002]

3. Olokoba, A.B., Obateru, O.A., Olokoba, L.B. (2012) Type 2 diabetes mellitus: a review of current trends. Oman Medical Journal.; 27(4): 269. [DOI:10.5001/omj.2012.68]

4. Shaw, J.E., Sicree, R.A., Zimmet, P.Z. (2010). Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Research and Clinical Practice. 87(1): 4-14. [DOI:10.1016/j.diabres.2009.10.007]

5. Javanbakht, M,. Mashayekhi, A,. Baradaran, H.R,. Haghdoost, A,. Afshin, A. (2015). Projection of diabetes population size and associated economic burden through 2030 in Iran: evidence from micro-simulation Markov model and Bayesian meta-analysis. PloS One. 10(7): e0132505. [DOI:10.1371/journal.pone.0132505]

6. Sicree, R,. Shaw, J,. Zimmet, P,. Heart, B.I. (2010).The global burden. Diabetes and impaired glucose tolerance Baker IDI Heart and Diabetes Institute.

7. Boulton, A.J. Vinik, A.I,. Arezzo, J.C,. Bril, V,. Feldman, E.L,. Freeman, R,. Malik, R.A,. Maser,R.E,. Sosenko, J.M,. Ziegler, D. (2005). Diabetic neuropathies: a statement by the American Diabetes Association. Diabetes Care. 28(4): 956-62. [DOI:10.2337/diacare.28.4.956]

8. Vinik, A.I,. Nevoret, M.L,. Casellini, C,. Parson, H. (2013).Diabetic neuropathy. Endocrinology and Metabolism Clinics. 42(4): 747-87. [DOI:10.1016/j.ecl.2013.06.001]

9. Rathur, H.M,. Boulto, A.J. (2007). The neuropathic diabetic foot. Nature Reviews Endocrinology. 3(1): 14-25 [DOI:10.1038/ncpendmet0347]

10. Ites, K.I,. Anderson, E.J,. Cahill, M.L,. Kearney,J.A,. Post, E.C,. Gilchrist, LS. (2011). Balance interventions for diabetic peripheral neuropathy: a systematic review. Journal of Geriatric Physical Therapy. 34(3): 109-16. [DOI:10.1519/JPT.0b013e318212659a]

11. Menz, H.B,. Lord, S.R,. St George, R,. Fitzpatrick, RC. (2004). Walking stability and sensorimotor function in older people with diabetic peripheral neuropathy. Archives of Physical Medicine and Rehabilitation. 85(2): 245-52. [DOI:10.1016/j.apmr.2003.06.015]

12. Volpato, S,. Leveille, S.G,. Blaum, C,.Fried, L.P,. Guralnik, J.M. (2005). Risk factors for falls in older disabled women with diabetes: the women's health and aging study. The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 60(12): 1539-45. [DOI:10.1093/gerona/60.12.1539]

13. Duby, J.J,. Campbell, R.K,. Setter, S.M,. White, J.R,. Rasmussen, K.A. (2004). Diabetic neuropathy: an intensive review. American Journal of Health-System Pharmacy. 61(2): 160-73. [DOI:10.1093/ajhp/61.2.160]

14. Yamamoto, R,. Kinoshita ,T,. Momoki, T,. Arai, T,. Okamura, A,. Hirao, K,. Sekihara, H. (2001). Postural sway and diabetic peripheral neuropathy. Diabetes Research and Clinical Practice. 52(3): 213-21. [DOI:10.1016/S0168-8227(01)00236-4]

15. Trikkalinou, A,. Papazafiropoulou, A.K,. Melidonis, A. (2017) Type 2 diabetes and quality of life. World Journal of Diabetes. 8(4): 120. [DOI:10.4239/wjd.v8.i4.120]

16. Norris, S.L,. Zhang, X,. Chowdhury, F.M,. Zhang, P. (2004). Health related quality of life measured by SF-36 for adults with diabetes: a meta-analysis. Ottawa: Cochrane Collaboration. 111.

17. Wexler,D.J,. Grant, R.W,. Wittenberg, E,. Bosch, J.L,. Cagliero, E,. Delahanty, L,. Blais, M.A,. Meigs, J.B. (2006). Correlates of health-related quality of life in type 2 diabetes. Diabetologia. 49(7): 1489-97. [DOI:10.1007/s00125-006-0249-9]

18. Boulé, N.G,. Haddad, E,. Kenny, G.P,. Wells, G.A,. Sigal, R.J. (2001)Effects of exercise on glycemic control and body mass in type 2 diabetes mellitus: a meta-analysis of controlled clinical trials. Journal of the American Medical Association. 286(10): 1218-27 [DOI:10.1001/jama.286.10.1218]

19. Stel, V.S,. Smit, J.H,. Pluijm, S.M,. Lips, P. (2003). Balance and mobility performance as treatable risk factors for recurrent falling in older persons. Journal of Clinical Epidemiology. 56(7): 659-68. [DOI:10.1016/S0895-4356(03)00082-9]

20. Song, C.H,. Petrofsky, J.S,. Lee, S.W,. Lee, K.J,. Yim, J.E. (2011). Effects of an exercise program on balance and trunk proprioception in older adults with diabetic neuropathies. Diabetes Technology and Therap‌eutics. 13(8): 803-11. [DOI:10.1089/dia.2011.0036]

21. Tinetti, M.E. (2003). Preventing falls in elderly persons. New England Journal of Medicine. 348(1): 42-9. [DOI:10.1056/NEJMcp020719]

22. da Silva, C.A,. Ribeiro, J.P,. Canto, J.C,. da Silva, R.E,. Junior, G.B,. Botura, E,. Malschitzky, M.A. (2012).High-intensity aerobic training improves endothelium-dependent vasodilation in patients with metabolic syndrome and type 2 diabetes mellitus. Diabetes Research and Clinical Practice. 95(2): 237-45. [DOI:10.1016/j.diabres.2011.09.034]

23. American College of Sports Medicine. (2013) ACSM's guidelines for exercise testing and prescription. Lippincott Williams & Wilkins. 381.

24. Colberg, S.R, . Sigal, R.J,. Yardley, J.E,. Riddell, M.C,. Dunstan, D.W,. Dempsey, P.C, .Horton, ES, . Castorino, K,. Tate, D.F. (2016) Physical activity/exercise and diabetes: a position statement of the American Diabetes Association. Diabetes Care. s39(11): 2065-79. [DOI:10.2337/dc16-1728]

25. Jelleyman, C,. Yates, T,. O'Donovan, G,. Gray, L.J,. King, J.A,. Khunti, K,. Davies, M.J. (2015). The effects of high‐intensity interval training on glucose regulation and insulin resistance: a meta‐analysis. Obesity Reviews. 16(11): 942-61. [DOI:10.1111/obr.12317]

26. Snowling, N.J,. Hopkins, W.G. (2006). Effects of different modes of exercise training on glucose control and risk factors for complications in type 2 diabetic patients: a meta-analysis. Diabetes Care. 29(11): 2518-27. [DOI:10.2337/dc06-1317]

27. Clark, M,. Lucett, S,. editors. (2010). NASM essentials of corrective exercise training. Lippincott Williams and Wilkins. 409

28. Herman, W.H,. Pop‐Busui, R,. Braffett, B.H,. Martin, C.L,. Cleary, P.A,. Albers, J.W,. Feldman, E.L,. DCCT/EDIC Research Group. (2012). Use of the Michigan Neuropathy Screening Instrument as a measure of distal symmetrical peripheral neuropathy in type 1 diabetes: results from the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications. Diabetic Medicine. 29(7): 937-44. [DOI:10.1111/j.1464-5491.2012.03644.x]

29. Feldman, E.L,. Stevens, M.J,. Thomas, P.K,. Brown. M.B,. Canal, N,. Greene, DA. (1994). A practical two-step quantitative clinical and electrophysiological assessment for the diagnosis and staging of diabetic neuropathy. Diabetes Care. 17(11): 1281-9. [DOI:10.2337/diacare.17.11.1281]

30. Kapoor, N,. David, K,. Saravanan, B. (2017). Approach to diabetic neuropathy. Current Medical Issues. 15(3): 189. [DOI:10.4103/cmi.cmi_38_17]

31. Church, T.S,. Blair, S.N,. Cocreham, S,. Johannsen, N,. Johnson, W,. Kramer, K,. Mikus, C.R,. Myers, V,. Nauta, M,. Rodarte, R.Q,. Sparks, L. (2010). Effects of aerobic and resistance training on hemoglobin A1c levels in patients with type 2 diabetes: a randomized controlled trial. Journal of the American Medical Association. 304(20): 2253-62. [DOI:10.1001/jama.2010.1710]

32. Lee, K,, Lee, S,. Song, C. (2013). Whole-body vibration training improves balance, muscle strength and glycosylated hemoglobin in elderly patients with diabetic neuropathy. The Tohoku Journal of Experimental Medicine. 231(4): 305-14. [DOI:10.1620/tjem.231.305]

33. Hirosaki, M,. Ohira, T,. Kajiura, M,. Kiyama, M,. Kitamura, A,. Sato, S, Iso, H. (2013). Effects of a laughter and exercise program on physiological and psychological health among community‐dwelling elderly in Japan: Randomized controlled trial. Geriatrics and Gerontology International. 13(1): 152-60. [DOI:10.1111/j.1447-0594.2012.00877.x]

34. Snowling, N.J,. Hopkins, W.G. (2006). Effects of different modes of exercise training on glucose control and risk factors for complications in type 2 diabetic patients: a meta-analysis. Diabetes Care. 29(11): 2518-27. [DOI:10.2337/dc06-1317]

35. Umpierre, D,. Ribeiro, P.A,. Kramer, C.K,. Leitão, C.B,. Zucatti, A.T,. Azevedo, M.J, Gross, J.L,. Ribeiro, J.P,. Schaan, B.D. (2011). Physical activity advice only or structured exercise training and association with HbA1c levels in type 2 diabetes: a systematic review and meta-analysis. Journal of the American Medical Association. 305(17): 1790-9. [DOI:10.1001/jama.2011.576]

36. Yavari, A,. Najafipoor, F,. Aliasgarzadeh, A,. Niafar, M,. Mobasseri, M. (2012).Effect of aerobic exercise, resistance training or combined training on glycaemic control and cardiovascular risk factors in patients with type 2 diabetes. Biology of Sport. 29(2): 135-143. [DOI:10.5604/20831862.990466]

37. Kluding, P.M,. Pasnoor, M,. Singh, R,. Jernigan, S,. Farmer, K,. Rucker, J,. Sharma, N.K,. Wright, D.E. (2012).The effect of exercise on neuropathic symptoms, nerve function, and cutaneous innervation in people with diabetic peripheral neuropathy. Journal of Diabetes and Its Complications. 26(5): 424-9. [DOI:10.1016/j.jdiacomp.2012.05.007]

38. Ahn, S,. Song, R. (2012). Effects of tai chi exercise on glucose control, neuropathy scores, balance, and quality of life in patients with type 2 diabetes and neuropathy. The Journal of Alternative and Complementary Medicine. 18(12): 1172-8. [DOI:10.1089/acm.2011.0690]

39. Dixit, S,, Maiya, A.G,. Shastry, B.A. (2014). Effect of aerobic exercise on peripheral nerve functions of population with diabetic peripheral neuropathy in type 2 diabetes: a single blind, parallel group randomized controlled trial. Journal of Diabetes and Its Complications. 28(3): 332-9. [DOI:10.1016/j.jdiacomp.2013.12.006]

40. Knight J, Nigam Y, Jones A. Effects of bedrest 1: cardiovascular, respiratory and haematological systems. Nursing Times. 2009 May 28;105(21):16-20.

41. Booth FW, Roberts CK, Laye MJ. Lack of exercise is a major cause of chronic diseases. Comprehensive Physiology. 2011 Jan;2(2):1143-211 [DOI:10.1002/cphy.c110025]

42. Rüger, L.J,. Irnich, D,. Abahji, T.N,. Crispin, A,. Hoffmann, U,. Lang, P.M. (2008). Characteristics of chronic ischemic pain in patients with peripheral arterial disease. Pain139(1): 201-8. [DOI:10.1016/j.pain.2008.03.027]

43. Kalra, S,. Jena, B.N,. Yeravdekar, R. (2018). Emotional and psychological needs of people with diabetes. Indian Journal of Endocrinology and Metabolism. 22(5): 696-704. [DOI:10.4103/ijem.IJEM_579_17]

44. Young-Hyman, D,. De Groot ,M,. Hill-Briggs, F,. Gonzalez, J.S,. Hood, K,. Peyrot, M. (2016).‌Psychosocial care for people with diabetes: a position statement of the American Diabetes Association. Diabetes Care. 39(12): 2126-40. [DOI:10.2337/dc16-2053]